ISSN 0862-5468 (Print), ISSN 1804-5847 (online) 

Ceramics-Silikáty 62, (2) 194 - 199 (2018)


MICRO-CT IN TISSUE ENGINEERING SCAFFOLDS DESIGNED FOR BONE REGENERATION: PRINCIPLES AND APPLICATION
 
Bartoš Martin 1, 4, 5, Suchý Tomáš 2, Tonar Zbyněk 3, Foltán René 1, Hubálek Kalbáčová Marie 4
 
1 Institute of Dental Medicine, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague 2, Czech Republic
2 Department of Composites and Carbon Materials, Institute of Rock Structure and Mechanics, Academy of Sciences of the Czech Republic, Prague 8, Czech Republic
3 Department of Histology and Embryology and Biomedical Centre, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic
4 Institute of Pathological Physiology, First Faculty of Medicine, Charles University, Prague 2, Czech Republic
5 Institute of Anatomy, First Faculty of Medicine, Charles University, Prague 2, Czech Republic

Keywords: Micro-CT, Tissue engineering scaffold, Bone regeneration, Biomaterials, 3D analysis
 

Micro-CT (micro-computed tomography) is a modern preclinical imaging method allowing non-destructive visualizations and structure analysis yielding at a resolution of a few micrometres. Tissue engineering scaffolds are a promising treatment for bone defects. Micro-CT application for the evaluation of tissue engineering scaffolds for bone surgery and traumatology application is increasing, which comprises in vitro, in vivo and ex vivo studies. Micro-CT itself is not able to replace conventional approaches completely, such as scanning electron microscopy (SEM) or histological examination, but it may offer important benefits regarding non-destructive approach, direct 3D model structure analysis, and visualization and time efficacy. The overview presented herein focuses on a micro-CT application in the field of tissue engineering scaffolds aimed at bone regeneration.


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doi: 10.13168/cs.2018.0012
 
 
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