Ceramics-Silikáty 66, (3) 274 - 279 (2022) |
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IN VITRO HYDROXYAPATITE FORMING ABILITY OF DICALCIUM SILICATE PREPARED FROM LOCAL RAW MATERIALS AND SINTERED AT 1050 ° C
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Chehlatt Sihem 1, Zohra Mezahi Fatima 2, Harabi Abdelhamid 3, Oudadesse Hassane 4
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1 Bio-engineering Laboratory, Higher National School of Biotechnology Toufik Khaznadar (ENSB), 25000 Constantine, Algeria.
2 Physics and Chemistry of Materials Laboratory, Department of Physics, Mohamed Boudiaf University, 28000, Msila, Algeria.
3 Department of Physics, Constantine University 1, 25000 Constantine, Algeria.
4 Unite Sciences Chimiques de Rennes, Universite de Rennes 1, Rennes, France.
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Keywords: Bioceramics, In vitro tests, Bioactivity, Simulated body fluid
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In this study, Ca₂SiO₄ powders were synthesised using solid state reaction. The starting powders were sintered at 1050 ° C for 2 h. Moreover, the in vitro bioactivity of β- Ca₂SiO₄ was investigated by soaking the powders in a simulated body fluid (SBF) for various time periods to analyse the growth of hydroxyapatite (HA) on the surface of these powders. The synthesised powders were characterised by scanning electron microscopy (SEM), X-ray diffraction (XRD), Fourier transform infrared (FTIR), and Inductively Coupled Plasma-Optical Emission Spectroscopy (ICP-OES) analysis. The simulated body fluid results showed that the β- Ca₂SiO₄ powders had good bioactivity to induce hydroxyapatite formation on their surface The results obtained showed that (HCA) can be formed on the surface of β- Ca₂SiO₄ soaked in the SBF solution for 1 day, and a continuous layer of dense HCA deposits covered the surface of β- Ca₂SiO₄ powders after 3 days of soaking in the SBF solution. Finally, the results obtained suggest that β- Ca₂SiO₄ ceramics are promising candidates for bone regeneration. |
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doi: 10.13168/cs.2022.0023
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