Ceramics-Silikáty 55, (1) 49 - 53 (2011) |
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PREPARATION OF BIOACTIVE NANOSTRUCTURE SCAFFOLD WITH IMPROVED COMPRESSIVE STRENGTH |
Tavangarian F., Emadi R. |
Department of Materials Engineering,
Isfahan University of Technology (IUT), Isfahan 84156-83111, Iran
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Keywords: Nanostructure materials, Bioactive glass, Ceramics, Hydroxyapatite, Scaffolds |
Highly porous scaffolds with open structure are today the best candidates for bone substitution to ensure bone oxygenation
and angiogenesis. In this study, we developed a new route to enhance the compressive strength of porous hydroxyapatite
scaffold made of natural bone. Briefly, the spongy bone of an adult bovine was extracted, annealed, and coated by a
nanostructure bioactive glass layer to be subsequently sintered at different temperatures. The apatite formation ability on the
surfaces of the coated scaffolds was investigated by standard procedures. Our results showed that the scaffold and coating
microstructure consisted of the grains smaller than 100 nm. These nanostructures improved the compressive strength and
bioactivity of highly porous scaffold. The results showed that with increasing the sintering temperature, the compressive
strength of scaffolds increased while their in vitro bioactivity decreased. |
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